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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 29, 1999 - Issue 14
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Original Articles

The Synthesis of New Bronchodilator Prodrugs

Mortimer H. Adams Department of Chemistry, University of the Western Cape, Private Bag X17, Bellville, 7530, Republic of South Africa
,
Farouk Ameer Department of Chemistry, University of the Western Cape, Private Bag X17, Bellville, 7530, Republic of South Africa
,
Ivan R. Green Department of Chemistry, University of the Western Cape, Private Bag X17, Bellville, 7530, Republic of South Africa
&
James A. Syce Department of Pharmacology, University of the Western Cape, Private Bag X17, Bellville, 7530, Republic of South Africa
Pages 2419-2430 | Received 19 Jan 1999, Published online: 17 Sep 2007
 
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Abstract

Prodrug 14 has been synthesized to investigate its lung accumulating property while prodrugs 19, 20 and 22 incorporating structural features of 14 have been prepared for evaluation as bronchodilatory agents.

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