A Convenient Preparation of (2SR,3S)-3-Amino-2-hydroxy-4-phenylbutanoic Acid; an Important Peptide Bond Isostere: Synthetic Communications: Vol 29, No 14

Synthetic Communications

An International Journal for Rapid Communication of Synthetic Organic Chemistry

Volume 29, 1999 - Issue 14

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Abstract

We present an efficient synthesis of N-Z-(2SR,3S)-3-amino-2-hydroxy-4-phenylbutanoic acids by hydroxylation of an enolate derived from methyl (3S)-N-Z-3-amino-4-phenylbutanoate with oxodiperoxymolybdenum (pyridine) (hexamethyl phosphoric triamide) complex (MoOPH).

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A Convenient Preparation of (2SR,3S)-3-Amino-2-hydroxy-4-phenylbutanoic Acid; an Important Peptide Bond Isostere

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A Convenient Preparation of (2SR,3S)-3-Amino-2-hydroxy-4-phenylbutanoic Acid; an Important Peptide Bond Isostere

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