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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 29, 1999 - Issue 16
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Original Articles

Efficient Dehydration of Aldoximes to Nitriles with TiCl3(OTf)

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Pages 2747-2752 | Received 24 Sep 1998, Published online: 25 Sep 2007
 

Abstract

Aromatic, alicyclic, olefinic as well as heterocyclic aldoximes, were dehydrated to their corresponding nitriles with 0.15 molar equivalents of TiCl3(OTf) in sealed tube at 80°C in 85-97% yield.

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