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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 29, 1999 - Issue 16
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Original Articles

Investigation of the Mitsunobu Reaction of N-(2-Hydroxyethyl)-N′-Phenyl-Ureas

Taek Hyeon Kim Faculty of Applied Chemistry, Chonnam National University, Kwangju, 500-757, Korea
,
Gue-Jae Lee Faculty of Applied Chemistry, Chonnam National University, Kwangju, 500-757, Korea
&
Mi-Hyun Cha Faculty of Applied Chemistry, Chonnam National University, Kwangju, 500-757, Korea
Pages 2753-2758 | Received 06 Oct 1998, Published online: 25 Sep 2007
 
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Abstract

The Mitsunobu reaction of N-(2-hydroxyethyl)-ureas 1 using PPh3 and EtO2CN[dbnd]NCO2Et led to the mixture of N- and O-alkylation products or a single isomer depending on the substrates.

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