Synthesis of 1-(5-Methylisoxazole-3-yl)-5-Aryl-Tetrazoles and its Pyrolysis

Abstract

3-Aroylamino-5-methylisoxazoles (2) were obtained by the reaction of 3-amino-5-methylisoxazole (1) with different aroyl chlorides. These amides on reaction with phosphorous pentachloride followed by sodium azide yielded 1-(5-methylisoxazole-3-yl)-5-aryltetrazoles (4). Pyrolysis of the tetrazoles thus obtained resulted in the formation of 3-aryl-6-acetyl(l,2-4)triazines (9).