A successful attempt to raise goat kids free of infection with caprine arthritis encephalitis virus in an endemically infected goat herd

Abstract

Goat kids from a herd endemically infected with caprine arthritis encephalitis (CAE) virus were raised according to 3 methods. One group of ten goat kids was removed from infected does at birth before suckling or licking by the doe could occur (snatch birth techique). Kids were fed on goat colostrum, which had been heated to 57°C for ten minutes and then held in a thermos flask for one hour. Subsequently the kids were fed reconstituted spray dried cows' milk powder. They were raised apart from infected goats with separation maintained by a wire fence. Contact occurred across-the-fence. Passively acquired serum antibody to CAE virus was detected in some kids at two to three months of age. Nine of the ten goats were negative for serum antibody to CAE virus when tested at 5–6, 9 and 12 months of age. One goat was positive at three and nine months of age but was negative when tested at 12 months of age.

A second group of four kids was removed at birth and fed heat-treated goat colostrum, followed by milk from CAE virus-infected does. All four kids became infected with CAE virus; they developed serum antibody to CAE virus between 5–6 and 9 months of age.

A third group of two kids was not removed from their infected dams. Both kids were infected at 5–6 and 9 months of age.