Mortality in lambs and cattle following the administration of phenothiazine

Abstract

Extract

Phenothiazine (thiodiphenylamine) has been regarded as comparatively non-toxic for sheep although abortion in ewes dosed late in pregnancy has been recorded by Hungerford and Howe (1944). Whitlock et al. (1945) described a severe mortality in lambs within one to two weeks, of phenothiazine therapy. Post-mortem examination revealed anaemia, fatty degeneration of the liver and anasarca.