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Abstract
Extract
Mannosidosis, a lethal inherited neurological disease associated with a deficiency of the lysosomal enzyme α-mannosidase (CitationHocking et al., 1972) has been described clinically as affecting Angus calves usually in their firstyear of life (CitationWhittem and Walker, 1957; CitationJolly, 1970, Citation1975). Although it has been suspected as a significant cause of neonatal mortality in herds at risk, figures and diagnosis supporting such an hypothesis have not been available.