The serology of calves vaccinated and challenged with Leptospira interrogans serotype pomona. I. Agglutination and complement fixation reactions

Summary

Calves vaccinated twice with one commercial pomona vaccine had serum MAT titres up to 1:300, warm CFT titres of 1:20 and cold CFT titres of up to 1:80. A second commercial vaccine did not elicit any detectable antibodies.

All calves, vaccinated as well as unvaccinated, showed a rapid rise in antibody levels, detectable with all three tests, following challenge with 38 × 108 pomona organisms.