Myeloproliferative disease in the cat: A granulocytic and megakaryocytic disorder

Abstract

The history, clinical, laboratory and post-mortem findings of a myeloproliferative disorder in a cat are described. The main features in peripheral blood were the presence of a high proportion of cells with abnormal morphology, and a large number of platelets, many of which were large and had immature staining characteristics. The abnormal cells had some characteristics of the granulocytic cell line. There was a proliferation of megakaryocytes within the spleen. The findings were characteristic of a granulocytic leukaemia with some evidence of a megakaryocytic myelosis.