Abstract
Extract
We are witnessing the beginnings of a revolution in the way in which vaccines are made, a revolution that has been stimulated by new molecular biology technology. Knowledge of the structure and function of immunising molecules is accumulating exponentially with the refinement of genetic manipulation techniques. Working in parallel are the immunologists who are beginning to understand the immune response in molecular detail. It appears inevitable that cheap synthetic molecularly defined preparations will supercede current whole-organism vaccines.