Animal medical genetics: a historical perspective on more than 50 years of research into genetic disorders of animals at Massey University

RD Jollya School of Veterinary Science, Massey University, Palmerston North, New Zealand

KE Dittmera School of Veterinary Science, Massey University, Palmerston North, New ZealandCorrespondence[email protected]

https://orcid.org/0000-0002-1813-2197

BR Jonesa School of Veterinary Science, Massey University, Palmerston North, New Zealand

AJ Wortha School of Veterinary Science, Massey University, Palmerston North, New Zealand

https://orcid.org/0000-0003-3800-4886

KG Thompsona School of Veterinary Science, Massey University, Palmerston North, New Zealand

AC Johnstonea School of Veterinary Science, Massey University, Palmerston North, New Zealand

DN Palmerb Faculty of Agriculture and Life Sciences, Lincoln University, Lincoln, New Zealand

NS Van de Waterc Department of Diagnostic Genetics, Auckland City Hospital, Auckland District Health Board, Auckland, New Zealand

KM Hemsleyd Childhood Dementia Research Group, South Australian Health and Medical Research Institute, Adelaide, Australia

DJ Garricke School of Agriculture & Environment, Al Rae Centre for Genetics and Breeding, Massey University, Hamilton, New Zealand

https://orcid.org/0000-0001-8640-5372

BG Winchesterf UCL Great Ormond Street Institute of Child Health, London, UK

SU Walkleya School of Veterinary Science, Massey University, Palmerston North, New Zealand;g Rose F. Kennedy Intellectual and Developmental Disabilities Research Center, Department of Neuroscience, Albert Einstein College of Medicine, Bronx, NY, USA

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ABSTRACT

Over the last 50 years, there have been major advances in knowledge and technology regarding genetic diseases, and the subsequent ability to control them in a cost-effective manner. This review traces these advances through research into genetic diseases of animals at Massey University (Palmerston North, NZ), and briefly discusses the disorders investigated during that time, with additional detail for disorders of major importance such as bovine α-mannosidosis, ovine ceroid-lipofuscinosis, canine mucopolysaccharidosis IIIA and feline hyperchylomicronaemia. The overall research has made a significant contribution to veterinary medicine, has provided new biological knowledge and advanced our understanding of similar disorders in human patients, including testing various specific therapies prior to human clinical trials.

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Animal medical genetics: a historical perspective on more than 50 years of research into genetic disorders of animals at Massey University

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Animal medical genetics: a historical perspective on more than 50 years of research into genetic disorders of animals at Massey University

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