Advanced search
Publication Cover
Xenobiotica
the fate of foreign compounds in biological systems
Volume 30, 2000 - Issue 6
Submit an article Journal homepage
150
Views
93
CrossRef citations to date
0
Altmetric
Research Article

Sulphation of resveratrol, a natural product present in grapes and wine, in the human liver and duodenum

C. De Santi Department of Neurosciences, Section of Pharmacology, Medical School, Via Roma 55, I-56126 Pisa, Italy
,
A. Pietrabissa Department of Oncology, Section of Surgery, Cisanello Hospital at University of Pisa, Cisanello, Pisa, Italy
,
R. Spisni Department of Surgery, Medical School, Via Roma 67, I-56126 Pisa, Italy
,
F. Mosca Department of Neurosciences, Section of Pharmacology, Medical School, Via Roma 55, I-56126 Pisa, Italy
&
G. M. Pacifici Department of Oncology, Section of Surgery, Cisanello Hospital at University of Pisa, Cisanello, Pisa, Italy
Pages 609-617 | Published online: 22 Sep 2008
 
Sample our Bioscience journals, sign in here to start your access, Latest two full volumes FREE to you for 14 days

Abstract

1. Resveratrol, a polyphenolic compound present in grapes and wine, has beneficial effects against cancer and protective effects on the cardiovascular system. It is present in the diet, and the hepatic and duodenal sulphation might limit the bioavailability of this compound. The aim was to study the sulphation of resveratrol in the human liver and duodenum. 2. A simple and reproducible radiometric assay for resveratrol sulphation was developed. It employed 3'-phosphoadenosine-5'-phosphosulphate-[35

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related Research Data

Pharmacokinetics, oral bioavailability, and metabolic profile of resveratrol and its dimethylether analog, pterostilbene, in rats
Source: Springer Science and Business Media LLC
DIFFERENTIAL EFFECTS ON GROWTH, CELL CYCLE ARREST, AND INDUCTION OF APOPTOSIS BY RESVERATROL IN HUMAN PROSTATE CANCER CELL LINES
Source: Elsevier BV
Resveratrol in human hepatoma HepG2 cells: metabolism and inducibility of detoxifying enzymes.
Source: HAL CCSD
Pharmacokinetic Consequences
Source: Springer Science and Business Media LLC
Metabolism and bioavailability of trans‐resveratrol
Source: Wiley
The flavonoids. A class of semi-essential food components: their role in human nutrition.
Source: S. Karger AG
Rat brain phenolsulfotransferase: partial purification and some properties.
Source: Elsevier BV
7-OH-flavone is sulfated in the human liver and duodenum, whereas 5-OH-flavone and 3-OH-flavone are potent inhibitors of SULT1A1 activity and 7-OH-flavone sulfation rate
Source: Informa UK Limited
Glucuronidation of resveratrol, a natural product present in grape and wine, in the human liver.
Source: Informa UK Limited
Can resveratrol supplement change inflammatory mediators? A systematic review and meta-analysis on randomized clinical trials
Source: Springer Science and Business Media LLC
Therapeutic potential of resveratrol: the in vivo evidence.
Source: Springer Science and Business Media LLC
Resveratrol: a natural compound with pharmacological potential in neurodegenerative diseases.
Source: Wiley
Synergism between resveratrol and other phytochemicals: Implications for obesity and osteoporosis
Source: Wiley
Method to assay the concentrations of phenolic constituents of biological interest in wines.
Source: American Chemical Society (ACS)
Sulphation of resveratrol, a natural compound present in wine, and its inhibition by natural flavonoids.
Source: Informa UK Limited
Activity in vitro of resveratrol on granulocyte and monocyte adhesion to endothelium.
Source: Oxford University Press (OUP)
Resveratrol as an anti-inflammatory and anti-aging agent: mechanisms and clinical implications.
Source: Wiley

Linking provided by 

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.