Copper(II) Bromide: A Simple and Selective Monobromination Reagent for Electron‐Rich Aromatic Compounds

Abstract

Copper(II) bromide was found to be a simple and efficient reagent for monobromination of electron‐rich aromatic compounds at room temperature. The reaction proceeded smoothly with phenols, aryl alkyl ethers, and aromatic amines to afford the corresponding monobrominated product selectively in moderate to good yields.

Keywords:

• anilines
• aryl alkyl ethers
• bromination
• copper(II) bromide
• phenols

Acknowledgments

S. B. is thankful to the Department of Atomic Energy, Government of India, for a fellowship. We thank S. Chattopadhyay, head of the Bio‐Organic Division, Bhabha Atomic Research Centre (BARC), for his valuable suggestions in preparing the manuscript.