Albumin-based biomaterial for lung tissue engineering applications

ABSTRACT

The role of albumin-based biomaterials in tissue engineering (TE) cannot be overemphasized. The authors review the role of albumin in lungs scaffold grafting, which promotes cell seeding. Albumin grafted on decellularized lungs scaffold is presented as a great support material for cell-tissue interaction as well as for ease in attachment, growth, and differentiation when seeded with different types of cells. Albumin scaffold fabrication from different sources is a promising approach that may facilitate medical treatments from bench-to-bed, although the role of this scaffold in lungs surfactant proteins regeneration and binding needs to be fully elucidated.

GRAPHICAL ABSTRACT

KEYWORDS:

• Albumin
• lungs and biomaterial
• regenerative medicine
• scaffold
• tissue engineering