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Articles

Polymeric microgels for bone tissue engineering applications – a review

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Pages 381-397 | Received 15 Oct 2018, Accepted 13 Jan 2019, Published online: 03 Feb 2019
 

Abstract

Microgels have recently gained exposure as a potential scaffold either alone or in combination with other scaffold for bone tissue engineering. Microgel has been defined as a small size particle of cross linked polymer chains with the ability of swelling and holding the large amount of solvent. This review summarizes the microgel based scaffolds specifically for bone tissue engineering. Microgels for growth factor delivery, cell transplantation and hybrid scaffold synthesis have been discussed in details. The success in recreating potential bone regenerative scaffold have been explored for clinical applications, future perspectives and its concurrent view has been deliberated in detail.

Graphical Abstract

Acknowledgements

The author acknowledges the University Grant Commission (Govt of India) for a senior research fellowship.

Disclosure statement

No potential conflict of interest was reported by the authors.

Additional information

Funding

The RV acknowledges the GSBTM [GSBTM/MD/Projects/SSA/1431/2014-15] for providing the financial support.

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