Lanthanide(III) Complexes with a Schiff Base Derived from 4-Aminohippuric Acid and 2-Thiophenealdehyde: Synthesis and Mouse Sperm Inhibition Activity

Abstract

Twelve lanthanide(III) complexes, Ln(TBG)₃. nH₂O [where Ln = La, Ce, Pr, Sm, Eu, Gd, Tb, Dy, Ho, Er, Yb, n = 3; Ln = Nd, n = 4; HTBG = 4-(2′-thiophenealdiminobenzoyl)glycine], were synthesized and characterized by elemental analyses, magnetic moment and molar conductance measurements, IR, UV and ¹H NMR spectra as well as TGA and DSC methods. Preliminary pharmacological tests showed mouse-sperm inhibition activity for the samarium complex.