Synthesis, Characterisation, Electrochemistry and Biological Activity of Ruthenium(III) Complexes Containing N.S Donor Ligands and Triphenylphosphine or Triphenylarsine

Abstract

Several new hexa-coordinated low-spin d⁵ ruthenium(III) complexes of the type [RuX₂(TSC)(EPh₃)₂] (where X = Cl or Br; H-TSC = benzaldehyde thiosemicarbazone, cinnamaldehyde thiosemicarbazone, thiophene-2-carboxaldehyde thiosemicarbazone and 2-furaldehyde thiosemicarbazone, E = P or As) have been synthesised by the reactions of [RuX₃(EPh₃)₃] or [RuBr₃(PPh₃)₂(MeOH)] with the various thiosemicarbazones. All the new complexes were characterised using various physico-chemical methods such as elemental analysis, spectral (IR, UV-VIS, EPR), magnetic moment and cyclic voltammetry data. In all these complexes, the thiosemicarbazones are bonded to the central ruthenium ion through the thiolato sulphur, after deprotonation, and the azomethine nitrogen. The antibacterial activity of some of the ligands and their complexes were also tested against two species of bacteria.

Referee I: M. J. Clarke

Referee II: M. B. Sponsler

Notes

Referee I: M. J. Clarke

Referee II: M. B. Sponsler