Synthesis, Characterisation and Biological Role of Anions (Nitrate, Sulphate, Oxalate and Acetate) in Co(II), Cu(II) and Ni(II) Metal Chelates of Some Schiff Base Derived Amino Acids

Abstract

Biologically active amino acid (alanine, glycine and tyrosine) derived Schiff base ligands and their Co(II), Cu(II) and Ni(II) metal chelates having the same metal atom but different cations (e.g., nitrate, sulphate, oxalate or acetate) have been synthesised and characterised by their physical, spectral and analytical data. The role of anions in these biologically active metal chelates against the bacterial species Staphylococcus aureus: Escherichia coli, Klehsiella pneumonae, Proteus vulgarus and Pseudomonas aeruginosa has been investigated and reported.