Crystal structures and antibacterial activities of two enoxacin based compounds

Abstract

Hydrothermal reactions of Cu(ClO₄)₂ · 6H₂O and Cu(SO₄)₂ · 5H₂O with enoxacin yielded two compounds, (H₂-Eno) · ClO₄ (1) and [Cu(H-Eno) · (H₂O)₂ · SO₄] · 2H₂O (2). Their solid-state structures have been characterized by elemental analysis, IR spectroscopy and single crystal X-ray diffraction analyses. Compounds 1 and 2 were screened for antibacterial activity against Staphylococcus aureas, Escherichia coli, Pseudomonas aeruginos and Candida albicans.

Keywords:

• Enoxacin
• Crystal structure
• Hydrothermal syntheses
• Copper complex
• Enoxacin perchlorate

Acknowledgement

This work was supported by the Doctor Foundation of Hunan University of Science and Technology (E55106).