Hydrothermal syntheses, crystal structures and antibacterial activities of two transition metal complexes with ciprofloxacin

Abstract

Hydrothermal reactions of ciprofloxacin with Co(OH)₂, and with oxalate and Fe(OH)₃, yield [Co(Cip)₂] · 2H₂O (1) and [Fe(H-Cip) · (C₂O₄)] · (H₂Cip) · 5H₂O (2), which were characterized by elemental analysis, IR and single crystal diffraction analyses. Compounds 1 and 2 were screened for antibacterial activities against Staphylococcus aureas, Escherichia coli, Candida albicans and Pseudomonas aeruginosa.

Keywords:

• Ciprofloxacin
• Iron
• Cobalt
• Crystal structure
• Oxalate
• Antibacterial activity

Acknowledgement

This work was supported by the Doctor Foundation of Hunan University of Science and Technology (E55106).