A supramolecular optic receptor for selective recognition CDP in neutral aqueous solution

Abstract

We designed and synthesized a Cu-coordination complex based on a seven-membered amide cycle and studied its binding ability with nucleotides (cytidine 5′-monophosphate (CMP), cytidine 5′-diphosphate (CDP), cytidine 5′-triphosphate (CTP), cytidine d-5′-monophosphate (dCMP), and thymidine d-5′-monophosphate (dTMP)) by UV-Vis spectroscopy. Results indicate that the compound shows the highest binding ability with CDP among the studied nucleotides and can selectively and strongly bind nucleotides in neutral aqueous solution. The compound can be used as optical receptor for the detection of CDP.

Keywords:

• Optic receptor
• Nucleotides
• Recognition
• Supramolecular interaction

Acknowledgment

This work was supported by projects 20371028 and 20671052 from the National Natural Science Foundation of China.