Synthesis, characterization, EDX, thermal, antioxidant, antibacterial, topographical, and gas adsorption studies of supramolecular tetraammoniumplatinate

Abstract

Reaction of K₂PtCl₄ with N-alkyl-N-benzyl-N,N-dimethyl ammonium chloride (n = 8, 10, 12 and 14 for alkyl) yielded supramolecular bis(benzyldimethylalkylazaniumyl) tetrachloroplatinumdiuide (metallobenzalkonium8 (MBK8), MBK10, MBK12, MBK14) characterized with spectroscopic and energy dispersive X-ray techniques. X-ray difraction powder analysis was performed which confirmed the crystalline nature of the compound. UV/Vis study performed in dimethylformamide, dimethylsulphoxide (DMSO)/H₂O, and DMSO/phosphate buffers under physiological conditions show stability of the supramolecular units, with [PtCl₄]²⁻. Zeta potential with particle size distribution of MBK8 obtained with DLS-confirmed agglomeration of the coordinate units. Thermal analysis by differential scattering calorimetric showed an effect of alkyl chain on their heat retention. For MBK8, topographical analysis and specific surface area were investigated with atomic force microscopy and nitrogen adsorption method, illustrating an outstanding alignment in arrays of ionic units, and an extent of apparent cross-sectional areas, respectively. Antioxidant and antibacterial activities were determined with 1–2,5-diphenyl-2-picrylhydrazyl-scavenging effect and Gram-positive and Gram-negative bacteria, respectively. The compounds exhibited activities for both scavenging and bacteria.

Keywords:

• MBK
• Adsorption
• Antioxidant
• Biological activity

Acknowledgements

Authors are thankful to the Vice Chancellor, Central University of Gujarat, Gandhinagar, for financial, infrastructural support, and experimental facilities.