Abstract
A functionalized calixarene with four platinum(II) centers was synthesized as a potential anticancer agent. The colorimetric cytotoxicity tests showed that it has amplified activity with respect to carboplatin against three different human carcinoma (non-small-cell lung, hepatocellular, and breast cancer) cell lines. It was most cytotoxic against the lung cancer cell line (IC50 = 2.6 μM).
Graphical Abstract
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