Abstract
A new copper(II) complex, [Cu(epoxy)(phen)(NO3)](NO3)·H2O (epoxy = 5,6-dihydro-5,6-epoxy-1,10-phenanthroline, phen = 1,10-phenanthroline), has been synthesized and characterized by elemental analysis, IR and UV–vis spectroscopy, and single crystal X-ray diffraction. The complex crystallized in a monoclinic system with space group P21/n, a = 13.3199(8) Å, b = 11.2917(7) Å, c = 16.0832(9) Å, α = 90°, β = 107.827(4)°, and γ = 90°. The complex cation possesses a distorted octahedral geometry, with Jahn–Teller distortion occurring in the CuN4O2 core. The binding interaction with calf thymus DNA (CT–DNA) was investigated by UV–vis and fluorescence spectroscopy, cyclic voltammetry, and viscometry. The results support a partially intercalative binding mode. Efficient cleavage of plasmid DNA by the complex was observed by gel electrophoresis.
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Acknowledgments
We are grateful to IIT-M, Chennai for providing instrumental facilities, including IR spectroscopy, X-ray crystallography, and fluorescence spectroscopy.
Disclosure statement
No potential conflict of interest was reported by the authors.