Syntheses, crystal structures, and antibacterial activity of oxidovanadium(V) and dioxidomolybdenum(VI) complexes derived from N′-(2-hydroxy-4-methoxybenzylidene)isonicotinohydrazide

Abstract

N’-(2-Hydroxy-4-methoxybenzylidene)isonicotinohydrazide (H₂L) was used as ligand to prepare new oxidovanadium(V) complex [VOL(OMe)(MeOH)] (1) and new dioxidomolybdenum(VI) complex [MoO₂L(MeOH)] (2). The two complexes were characterized on the basis of their FT-IR, UV, ¹H NMR spectra, and molar conductivity. Crystal structures of 1 and 2 have been determined by single crystal X-ray diffraction techniques, which show that the hydrazone ligand coordinates as a di-valent anion with its tridentate O, N, O donors derived from the enolic and phenolic oxygen and azomethine nitrogen. The V ion in 1 is in octahedral coordination, with three donors of the hydrazone ligand and with the remaining sites furnished by one deprotonated methanol oxygen, one neutral methanol oxygen, and one oxo oxygen. The Mo ion in 2 is in octahedral coordination, with three donors of the hydrazone ligand and with the remaining sites furnished by one neutral methanol oxygen and two oxo oxygen atoms. Molecular structures of 1 and 2 are stabilized by hydrogen bonds. The hydrazone and the complexes were screened for their antimicrobial activity and showed good activity.

Graphical Abstract

Keywords:

• Hydrazone
• oxidovanadium
• dioxidomolybdenum
• X-ray diffraction
• antibacterial

Additional information

Funding

We gratefully acknowledge the financial support by the Research Program of Science and Technology at Universities of Inner Mongolia Autonomous Region (NJZY19220 and NJZY19223), Inner Mongolia Key Laboratory of Photoelectric Functional Materials, Chifeng University Key Laboratory of Photoelectric Functional Materials, and Chifeng University Science and Research Creative Team.