Unprecedented cleavage of -N-N- bond of ligand and phenyl ring nitration during nitric oxide (NO) reactivity studies: new ruthenium nitrosyl complex and photoinduced liberation of NO

Abstract

A two-step procedure was used to make the ruthenium nitrosyl complex [Ru(L³)(PPh₃)(NO)Cl₂] (1a). The product generated when ligand L¹ and [Ru(PPh₃)₃Cl₂] reacted to an acidified nitrite solution treatment. Single-crystal X-ray diffraction was used to determine the crystal structure of (1a). Complex (1a) has a {Ru–NO}⁶ moiety in the Enemark–Feltham notation and was found to be diamagnetic in nature. Photolytic cleavage of metal-bound NO in (1a) was observed under ultraviolet light, and photoreleased free NO was trapped by reduced myoglobin. The amount of photoreleased NO was estimated by the Griess assay. DFT computations were also performed to authenticate the electronic properties of (1a).

Keywords:

• Ruthenium-nitrosyl complex
• crystal structure
• -N-N- bond cleavage
• ligand nitration
• Griess reaction assay

Supporting information

CCDC 973075 contains the supplementary crystallographic data for the complex (1a). These data can be obtained free of charge via http://www.ccdc.cam.ac.uk/conts/retrieving.html, or from the Cambridge Crystallographic Data Centre, 12 Union Road, Cambridge CB2 1EZ, UK; Fax: [phone]; or E-mail: [email protected].

Disclosure statement

No potential conflict of interest was reported by the authors.

Additional information

Funding

KG is thankful to CSIR, New Delhi, India, for financial assistance No. 01(2942)/18/EMRII dated 01-05-2018). SK is thankful to CSIR, New Delhi. SS is grateful to DST/INSPIRE/2017/IF170967. KM is thankful to UGC, RK, and AR is thankful to IIT Roorkee for their fellowship.