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Abstract
High pressure liquid chromatography (HPLC) has proven to be one of the most useful techniques available to the chemist for separating complex mixtures of organic substances. The range of compounds that have been successfully separated by HPLC continues to expand at an extremely rapid rate. Within the last five years, HPLC has been applied to increasingly complex separations in the field of natural products chemistry. This article reviews a number of separations in selected are as of natural products chemistry. While it is not an exhaustive survey of the literature, it does indicate the variety of separations already achieved and hopefully will suggest additional areas of utility.