Separation of Optical Isomers as Diastereomeric Derivatives by High Performance Liquid Chromatography

Tomozoh Tamegai Research Laboratories, Eisai Co., Ltd., 4-6-10, Koishikawa, Bunkyo-Ku, Tokyo, Japan

Masahiko Ohmae Research Laboratories, Eisai Co., Ltd., 4-6-10, Koishikawa, Bunkyo-Ku, Tokyo, Japan

Kiyoshi Kawabe Research Laboratories, Eisai Co., Ltd., 4-6-10, Koishikawa, Bunkyo-Ku, Tokyo, Japan

Munemitsu Tomoeda Research Laboratories, Eisai Co., Ltd., 4-6-10, Koishikawa, Bunkyo-Ku, Tokyo, Japan

Abstract

Optical isomers occuring widely in nature, display different biochemical and pharmacological effects against their enantiomeric isomers. Therefore, it is very important to distinguish or resolve enantiomers, especially in biochemical and pharmaceutical applications.

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Separation of Optical Isomers as Diastereomeric Derivatives by High Performance Liquid Chromatography

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Separation of Optical Isomers as Diastereomeric Derivatives by High Performance Liquid Chromatography

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