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Abstract
The use of hydroxyl exchange resins (Dowex AG 1-X8 and AG 501-X8) as a component in the preparative clean up of biological samples for HPLC sugar and polyhydric alcohol analysis is inappropriate. On a weight specific basis, these resins bind 95–100% of monosaccharides (fructose and glucose), 45–85% of disaccharides (sucrose and trehalose) and 15–50% of polyhydric alcohols (glycerol and adonitol) present in sample solutions.