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Abstract
Trinitrobenzene sulfonic acid, 2,4-dinitrofluorobenzene and 2-chloro-3,5-dinitropyridine were compared in terms of properties relevant to use as precolumn derivatization labels for amino compounds. This included consideration of chemical characteristics as well as purely detector oriented behavior. Trinitrobenzene sulfonic acid appears to be superior in all respects, yielding the most detectable derivatives with minimum production of interfering by-products.