Abstract
A method has been developed to assay tiaprofenic acid in human plasma. The technique is rapid, specific and sensitive, being capable of detecting 0.5′ μg ml−1 and requiring only 200 μl of plasma for a single assay.
Samples are deproteinized, extracted into chloroform and then, after evaporation of the chloroform and reconstitut ion in the mobile phase, are chromatographed by reverse phase liquid chromatography.