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Abstract
The available techniques for the analysis of radiolabled TLC plates are described and compared, including the newest technique based on imaging proportional counters. The imaging systems offer a 100-fold improvement in sensitivity over conventional chromatogram scanners and can replace much of the analysis currently being done by plate scraping and scintillation counting. For most quantitative analysis, imaging systems offer superior speed and comparable or better accuracy when compared with scintillation counting. Large savings can be realized in sample preparation time, disposable supply costs, and liquid waste disposal.