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Abstract
Excretion patterns of urinary phenolic compounds were determined by means of chromatography with Sephadex G-10, with 4-aminoantipyrine for the detection of phenolic compounds.
Derivatization for phenolic compounds is based on a coupling reaction with 4-aminoantipyrine in the presence of sodium metaperiodate. The reaction is complete within a few minutes and, thus, provides a simple detection method.
Excretion patters of samples with normal subjects and patients of catecholamine-producing tumor were determined and the results were compared.
From the data obtained, this method is shown to be useful as a screening test of some catecholamine-producing tumors.