Separation of Mycotoxins, Polycyclic Aromatic Hydrocarbons, Quinones, and Heterocyclic Compounds on Cyclodextrin Bonded Phases: An Alternative LC Packing

Abstract

β-Cyclodextrin and γ-cyclodextrin chiral bonded phases were previously shown to be useful in the separation of enantiomers, diastereomers and structural isomers. In this work it is demonstrated that these stationary phases are also useful in more routine separations. As such, they provide an alternative to the popular reverse phase packings. Because the selectivity of cyclodextrin packings is often unique they can be used to compliment conventional columns, particularly when separating complex mixtures where peak overlap is a problem. The separation of several important classes of compounds is used to demonstrate the general utility of this packing.