Adsorption HPLC Investigation of Nitrogen-Bridged Compounds

A. Shalaby Institute of Pharmaceutical Chemistry Semmelweis Medical University, Budapest, Hungary

Zs. Budvári-Bárány Institute of Pharmaceutical Chemistry Semmelweis Medical University, Budapest, Hungary

Gy. Szasz Institute of Pharmaceutical Chemistry Semmelweis Medical University, Budapest, Hungary

K. Hankó-Novák Institute of Pharmaceutical Chemistry Semmelweis Medical University, Budapest, Hungary

I. Hermecz Institute of Pharmaceutical Chemistry Semmelweis Medical University, Budapest, Hungary

Abstract

Twenty two of tricyclic nitrogen bridged derivatives were examined by HPLC method in Zorbax SIL/chloroform–methanol system. Relationship between chemical structure (ring size, ring sequence, position of methyl substitution) and chromatographic behaviour is discussed.

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Adsorption HPLC Investigation of Nitrogen-Bridged Compounds

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Adsorption HPLC Investigation of Nitrogen-Bridged Compounds

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