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Abstract
A simple and specific high performance liquid chromatographic method has been developed for the determination of mercury-containing drugs. In most cases, an aliquot of the diluted sample is injected directly into a Zorbax ODS column and eluted with methanol-0.05 N ammonium acetate (3+2), pH 5.7, containing 0.01% 2-mercaptoethanol. Detection is accomplished by atomic absorption spectrophotometry with the aid of a specially designed apparatus for the generation of mercury vapor.