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Original Articles

Review of High-Performance Liquid Chromatography in the Assay of Endogenous Substances in Clinical Chemistry

Pages 2805-2825 | Published online: 19 Dec 2006
 

Abstract

There is a great potential for HPLC in assaying endogenous substances in the routine clinical chemistry laboratory. This technique coupled with sensitive detectors, can compete in certain instances with RIA and without the need for preparing antisera or labeling the antigen. Furthermore, it can detect small molecular heterogeneity.

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