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Abstract
A summary Is provided of most of Che reported derlvatizations that have been used for improved analyte detection in liquid chromatography with electrochemical detection (LCEC). These approaches include pre-column derivatizations and postcolumns chemical, photochemical or enzymatic reactions for oxidative EC detection. This review covers the literature up to early 1985, and includes information gathered from books, technical articles, previous reviews and scientific journal publications. Specific reagents, methods and instrumentation are described for those classes of compounds studied by derlvatization-LCEC, and suggestions for future experiments are included, where applicable. It is concluded that the future will likely Include the development of a great number of derivatizations which may be used in conjunction with LCEC for trace analysis.