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Abstract
The use of cyclobond-I solid phase extraction (SPE) cartridges in the analysis of sulfonamides was investigated. an aqueous solution of sulfonamides in 0.1 M potassium phosphate buffer (pH 4.0) was passed through the SPE cartridge. the sulfonamides which were retained on the cartridge by formation of inclusion complexes between the sulfonamides and B-cyclodextrin were eluted with 50% aqueous methanol. the eluate was directly analysed by High Performance Liquid Chromatograph with UV detection at 265nm.