Identification of Some Closely Related N-Carbamoyl-3,5-Dimethyl-4-Arylazopyrazoles by TLC

Abstract

Duet to the key role of arylazopyrazoles in biochemical sciences, interest has sprung up to achieve their resolution and identification by thin layer chromatographic technique. Present communication describes the resolution of some N-carbamoyl-3, 5-dimethyl-4-arylazopyrazoles on silica gel-G plates impregnated with various surfactants viz., 1% acetoacetanilide, 1% tritonX-100 and 1% tetrabutylammounium bromide. A correlation of R_f value with Hammett substituent constant (σ) is also interpreted.