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Abstract
The form of the flow velocity profile developed in a carrier liquid flowing in separation channel for focusing field-flow fractionation can be controlled by manipulating the shape of the channel cross-section. The velocity profiles established in modulated cross-sectional permeability channels under the conditions of isoviscous flow were described previously by using the approximate solution of Navier-Stokes equation. In this paper, the previous approach is compared with an exact solution. The theoretical resolution is calculated for the actual trapezoidal cross-section channels and compared with the experimentally achieved resolutions. A fair agreement between the calculated and experimental resolutions was obtained.