Silica Based Aminopropyl-Bonded Phase Trimethylsilylated with N-Trimethylsilylimidazole

Abstract

N-trimethylsilylimidazole is a suitable agent for the silanization of silica based amino phases, because it reacts selectively with silanol groups. the effect of trimethylsilylation is illustrated chromatographically in anhydrous heptane and in separations of sugar mixtures in the acetonitrile-water mobile phase.