Highly selective purification of ferulic acid from wheat bran using deep eutectic solvents modified magnetic nanoparticles

ABSTRACT

Fe₃O₄ nanoparticles (Fe₃O₄NPs) were prepared by chemical coprecipitation. Deep eutectic solvents (DESs) (ChCl/glycol, 1/2, n/n) were used to modify Fe₃O₄NPs. The obtained Fe₃O₄NPs and DESs–Fe₃O₄NPs were applied for purification of ferulic acid from wheat bran by magnetic solid-phase extraction (MSPE). The satisfactory extraction recoveries for ferulic acid (88.7%) were obtained by changing different washing and eluted solvents. The recovery of the proposed method at three spiked level analysis was 77.9–97.5%, with the relative standard deviation less than 4.5%. DESs–Fe₃O₄NPs showed good performance for ferulic acid and the proposed approach might offer a novel method for purifying complex samples.

KEYWORDS:

• Deep eutectic solvents
• ferulic acid
• magnetic nanoparticles
• magnetic solid-phase extraction

Funding

This research was supported by the Tianjin Municipal Natural Science Foundation of China (13JCYBJC42200), and it was also supported by the Hebei Province Science and Technology Program funded by Hebei Province Technology Department (15272804) and the Hebei Province Universities Science and Technology Program funded by Hebei Province Education Department (QN2016207).

Additional information

Funding

This research was supported by the Tianjin Municipal Natural Science Foundation of China (13JCYBJC42200), and it was also supported by the Hebei Province Science and Technology Program funded by Hebei Province Technology Department (15272804) and the Hebei Province Universities Science and Technology Program funded by Hebei Province Education Department (QN2016207).