https://orcid.org/0000-0003-2427-4615
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Abstract
Among the gastrointestinal tract cancers, the risk of colon cancer is strongly dependent on dietary factors. For the first time in the current review, all the original case-control studies, associated with the correlation between total dietary diversity score and colon cancer risk, were evaluated. In this regard, three databases, including PubMed/MEDLINE, Scopus, and Web of Sciences, were investigated to retrieve the related citations from 1990 until 2019. Among the included citations, three studies were finally included. In these included studies, the dietary diversity score was evaluated with 129-item and 800-item FFQs. Findings reveal that total dietary diversity can increase the risk of colon cancer in men, but not women; while, one study using 57-item FFQ reported the beneficial association of total dietary diversity with colon cancer among men. Significant demand for conducting more research to investigate the real mechanistic effects of dietary diversity on the risk of colon cancer development was demonstrated due to the inconsistent, questionable, and incomplete findings associated with the included studies.
Acknowledgments
This study is related to the project NO 1398/10565 from the Student Research Committee, Shahid Beheshti University of Medical Sciences, Tehran, Iran. We also appreciate the “Student Research Committee” and “Research & Technology Chancellor” at Shahid Beheshti University of Medical Sciences for their financial support of this study.
Conflict of Interest
The authors declare no conflict of interest.
Authors’ Contributions
Conceptualization: MJ, MB. Data curation: MB, AF. Formal analysis: MB, MJ. Investigation: FF. Methodology: FJ, MB. Project administration: HEZ, PMM. Supervision: HEZ, PMM. Validation: FH. Visualization: FH, FJ. Writing (original), draft preparation: MB, MJ, FJ. Writing—review and editing: AMK. All authors have read and approved the final submitted manuscript.