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Reports

Natural defense systems of fasting rats against tumor cells

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Pages 127-134 | Received 28 Oct 1987, Accepted 01 Aug 1988, Published online: 04 Aug 2009
 

Abstract

The effect of fastmg on naturally cytotoxic cells in rat liver and rat spleen was investigated. Neither fasting 100% (nor 50%) for eight days nor 100% overnight significantly reduced this natural cytotoxicity.

Target cells YAC‐1, P815, and WEHI‐164 cells were used in a chromium release assay. Assuming that YAC‐1 cells are preferentially killed by “true”; natural killer cells, P815 by macrophages, and WEHI‐164 by so‐called natural cytotoxic cells, our results indicate that none of these subsets of naturally cytotoxic cells are hampered or stimulated by the fasting regimens used.

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