Late onset Leber's Hereditary Optic Neuropathy

Abstract

Leber's Hereditary Optic Neuropathy is a mitochondrial genetic disorder that causes acute to subacute bilateral central loss of vision. It typically presents in young men in their second or third decade of life and onset later in life is rare. We describe a case of a 58-year-old man with late onset of LHON and discuss the importance of suspecting the diagnosis in appropriate cases.

KEYWORDS:

• Mitochondrial disorder
• genetics
• LHON
• optic neuropathy
• neuro-opthalmology