Neuro-Ophthalmic Presentation of Neuro-Sweet Disease

ABSTRACT

Acute febrile neutrophilic dermatosis (Sweet syndrome) is a systemic inflammatory condition usually associated with autoimmune or neoplastic processes and characterised by inflammatory dermatologic lesions such as erythematous plaques and papules associated with fever and leukocytosis. Neurological and ophthalmological involvement is rare. The authors describe an unusual case of Sweet syndrome associated with microscopic polyangiitis presenting with papilloedema, anterior uveitis, and skin rash. Years later, he developed acute posterior multifocal placoid pigment epitheliopathy. Treatment with immunosuppressive medications led to a relapsing remitting course with maximum benefit from use of steroids. The authors describe the difficulties in diagnosis and treatment of this rare case.

KEYWORDS:

• APMPPE
• microscopic polyangiitis
• neuro-Sweet
• papilloedema
• Sweet syndrome

Acknowledgements

The authors wish to thank the physicians from the rheumatology and pulmonology departments for their help in the management of this complicated case.

Declaration of interest

The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the article.