Cancer-associated Retinopathy Developing After 10 Years of Complete Breast Cancer Remission

ABSTRACT

A 73-year-old female with a past medical history of breast cancer, who 10 years earlier experienced complete remission, complained of bilateral visual field disturbances and photopsia, 2 months prior. Tumour recurrence and metastatic lesions were not found during the medical examination, but antibodies against recoverin were detected in her serum. Despite immunosuppressive treatment with prednisolone and plasmapheresis, rapid and diffuse degeneration of the patient’s photoreceptors and deterioration of her visual field were observed. This is a rare case of cancer-associated retinopathy with a long interval (10 years) between the diagnosis of the malignancy and visual loss.

KEYWORDS:

• Cancer-associated retinopathy
• recoverin
• breast cancer

Declaration of interest

The authors declare that there are no conflicts of interest. The authors alone are responsible for the writing and content of the article.

Additional information

Funding

H.S. was supported by the Japan Society for the Promotion of Science (JSPS) KAKENHI Grant Number [JP16K11319];