Invasive Fungal Sinusitis with Ophthalmological Complications: Case Series and Review of the Literature

ABSTRACT

Invasive fungal sinusitis can lead to dramatic complications in immunocompromised patients and requires prompt diagnosis. Here we report three cases with ophthalmological complications secondary to invasive fungal sinusitis in immunocompromised patients. From an ophthalmological point of view, these cases illustrate different clinical presentations, evolutions, complications, treatments, prognoses, and highlight different pathophysiological mechanisms. Diagnoses were delayed in all cases. In none of the cases did patients recover better vision than counting fingers at 24 months follow up, and two patients died. This case series highlights key points useful for quickly recognising this highly morbid infection in immunocompromised patients.

KEYWORDS:

• Fungal sinusitis
• optic neuropathy
• immunocompromised patients
• orbital apex syndrome
• ct scan
• magnetic resonance imaging

Declaration of interest statement

The authors report no conflict of interest.